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liver tox*******LiverTox ® provides up-to-date, unbiased and easily accessed information on the diagnosis, cause, frequency, clinical patterns and management of liver injury attributable to prescription and nonprescription medications and selected herbal and .Alpha lipoic acid is a natural occurring essential fatty acid that is synthesized .Acetaminophen is a widely used nonprescription analgesic and .

Allopurinol is a rare but well known cause of acute liver injury that has features of a .

(Among 37,929 Taiwanese persons with chronic liver disease started on statin .A liver biopsy showed multiple epithelioid granulomas and acute hepatic injury .Tamsulosin therapy is associated with a low rate of serum aminotransferase .Hepatotoxicity. Limited data are available on the potential hepatotoxicity of .

Dulaglutide is a recombinant DNA produced polypeptide analogue of human .Niacin, also known as nicotinic acid and vitamin B3, is a water soluble, essential .

LiverTox represents a collaborative effort by medical and scientific specialists to provide a central repository of clinical . LiverTox provides up-to-date, accurate and easily accessible information on the diagnosis, cause, frequency, patterns and management of liver injury from . LiverTox ® provides up-to-date, unbiased and easily accessed information on the diagnosis, cause, frequency, clinical patterns and management of liver injury . The LiverTox website is designed to be a practical and useful adjunct for the clinician confronting a patient with liver injury who is taking a medication that may be causative, and is a resource for .

LiverTox is a free online resource created by the NIDDK and the National Library of Medicine to help health care professionals recognize and diagnose liver injury . Rare instances of idiosyncratic liver injury have been reported in persons receiving the aminopenicillins including amoxicillin. Cases are characterized by a short latency period of a few days to as .LiverTox is a free online resource that provides evidence-based information on drug-induced liver disease. It covers about 700 medications, their patterns of liver damage, .LiverTox is a multilayered, informational, and interactive website with comprehensive and evidence-based information on drug, dietary supplement, and herbal-induced liver injury .

The DILIrank dataset consists of 1,036 FDA-approved drugs that are divided into four classes according to their potential for causing drug-induced liver injury (DILI).

Levetiracetam was approved for use in epilepsy in 1999 and current indications are as adjunctive therapy for partial onset seizures, generalized tonic-clonic seizures and myoclonic seizures in both . Isoniazid is the most reliable and most commonly used medication for tuberculosis. Isoniazid therapy is often associated with minor, transient and asymptomatic elevations in serum .

The oral cephalosporins are widely used in medicine for mild-to-moderate infections due to susceptible bacteria. The oral cephalosporins are generally well tolerated; adverse events can . The typical maintenance dose of adalimumab in adults is 40 mg subcutaneously every other week. Common side effects include injection site reactions, headache, nausea, abdominal discomfort, diarrhea, skin rash and fever. Rare but potentially severe side effects include bone marrow suppression, demyelinating disorder, severe . Rifampin (also referred to as rifampicin) is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. Rifampin is associated with transient and asymptomatic elevations in serum aminotransferase and bilirubin levels and is a well known cause of clinically . Doxycycline (dox" i sye' kleen) is a semisynthetic tetracycline that is used for mild-to-moderate infections due to susceptible organisms. Doxycycline, like other tetracyclines, is active against a wide spectrum of gram-positive and gram-negative bacteria as well as against several rickettsia, spirochetes, chlamydia and mycoplasma. Metformin is a first line agent for the treatment of type 2 diabetes that can be used alone or in combination with sulfonylureas, thiazolidinediones, incretin-based drugs, sodium glucose cotransporter-2 inhibitors, or other hypoglycemic agents. Metformin has not been linked to serum enzyme elevations during therapy and is an exceeding rare cause .

HHS. USA.gov. The clinical symptoms, signs and patterns of liver test abnormalities of drug induced liver injury can mimic virtually any form of liver disease – from acute viral hepatitis to gall stone disease with biliary obstruction, acute fatty liver and even chronic hepatitis and cirrhosis. There are no specific findings or laboratory . The amphetamines are indirect acting sympathomimetic amines and powerful central nervous system stimulants which are used in the therapy of attention deficit disorder, hyperactivity and narcolepsy. Amphetamines also have a potential for abuse and illicit forms of amphetamines constitute some of the most dangerous, but widely used .liver tox livertox.com LiverTox is also a living document that can be expanded as new medications and information become available. Finally, LiverTox also provides an opportunity to promote and participate in future research on DILI, a common and important but still poorly understood form of liver disease.

livertox.comLiverTox is a multilayered, informational, and interactive website with comprehensive and evidence-based information on drug, dietary supplement, and herbal-induced liver injury that is freely accessible to physicians, researchers, and the public. The website is particularly designed for use by physicians and healthcare professionals who might .

liver tox Valproate (val proe' ate) is a carboxylic acid derivative that appears to act by increasing brain levels of gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the human brain. .

由於此網站的設置，我們無法提供該頁面的具體描述。 Amoxicillin (a mox' i sil' in) is an orally available aminopenicillin antibiotic that has been available in the United States since 1980, for which currently more than 50 million prescriptions are filled yearly. Amoxicillin is used to treat mild to moderate infections caused by susceptible agents, such as (but not limited to) Escherichia coli, Hemophilus .

Isotretinoin is a retinoid and vitamin A derivative used in the treatment of severe acne and some forms of skin, head and neck cancer. Isotretinoin, like many retinoids, can lead to increase in serum aminotransferase levels, but, unlike acitretin and etretinate, isotretinoin has not been clearly implicated in cases of clinically apparent . Finally, LiverTox allows for submission of clinical cases of hepatotoxicity to the website, which will be added to a database that can be accessed and analyzed. LiverTox is an ambitious effort aimed not only at providing clinical information on DILI but also at stimulating and assisting future research into its cause, prevention, and treatment. Milk thistle (Silybum marianum) is an herb native to Europe, Asia Minor and Northern Africa that has been used widely to treat liver disease. Extracts of milk thistle seeds contain multiple flavanolignans, known collectively as silymarin, consisting largely of silybinin, silychristin and silydianin. In cell culture and animal models, silymarin . Terbinafine (ter' bin a feen) is a synthetic allylamine derivative that has potent activity against many dermatophytes that affect skin and nails, including Epidermophyton floccosum, Trichophyton mentagrophytes and Trichophyton rubrum. The antifungal activity of terbinafine is believed to be due to the selective inhibition of fungal .

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liver tox|livertox.com